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DeCS
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Descriptor English:
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Immunoglobulin Class Switching
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Descriptor Spanish:
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Cambio de Clase de Inmunoglobulina
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Descriptor Portuguese:
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Switching de Imunoglobulina
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Synonyms English:
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Class Switching, Immunoglobulin
Class Switchings
Class Switchings, Immunoglobulin
Immunoglobulin Class Switchings
Isotype Switchings
Switching, Class
Switching, Immunoglobulin Class
Switching, Isotype
Switchings, Class
Switchings, Immunoglobulin Class
Switchings, Isotype
Class Switching
Isotype Switching
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Tree Number:
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G05.344.401.501.450
G12.500.274.501.450
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Definition English:
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Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing. |
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History Note English:
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94
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Allowable Qualifiers English:
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Record Number:
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31391
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Unique Identifier:
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D017578
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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